Pulmonary endothelial barrier dysfunction is a hallmark of clinical pulmonary edema and contributes to the development of acute lung injury (ALI). Here we reported that ruscogenin...
Ruscogenin is a well-known compound for down-regulating nuclear factor kappa B (NF-κB), intercellular adhesion molecule-1 (ICAM-1), tissue factor (TF), inducible NO synthase (iNOS),...
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Herbalists may utilise Butcher’s Broom extract powder with conditions including chronic venous insufficiency, nocturnal calf-muscle spasms, itchy-heaviness or swelling of legs, oedema, varicose or...
The anti-elastase activity of ruscogenin helps to prevent the degradation of the perivascular components and thus reduce cell permeability. Ruscogenin also has vasoconstrictive properties via...
The principal class of active compounds are steroidal saponins, particularly neuroscogenin and ruscogenin. Probably, the Ruscus extract can cause contractions activating postjunctional alfa-1 and...












